Vidarabine monophosphate

  • Name: Vidarabine monophosphate
  • CAS: 29984-33-6
  • Purity: 99%
  • Description

    99% Purity Commercial production Vidarabine monophosphate 29984-33-6 with Cheapest Price

    • Molecular Formula: C10H14N5O7P
    • Molecular Weight: 347.224
    • Appearance/Colour: White crystalline powder. 
    • Vapor Pressure: 6.7E-27mmHg at 25°C 
    • Melting Point: 213 °C 
    • Boiling Point: 798.5 °C at 760 mmHg 
    • PKA: 1.86±0.10(Predicted) 
    • Flash Point: 436.7 °C 
    • PSA: 195.88000 
    • Density: 2.32 g/cm3 
    • LogP: -1.28180 

    Vidarabine monophosphate(Cas 29984-33-6) Usage

    Safety Profile

    Moderately toxic byintraperitoneal route. When heated to decomposition itemits very toxic fumes of POx and NOx.

    Application

    Vidarabine monophosphate has broad-spectrum anti-virus effect and can inhibit a variety of DNA viruses. It is mainly used to treat chronic hepatitis B and other viral infections, such as herpes zoster, herpes simplex and genital herpes. It has quick effect and clear curative effect. It is a common drug for clinical anti-virus treatment.

    InChI:InChI=1/C10H14N5O7P/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20)/p-2/t4-,6-,7+,10-/m1/s1

    29984-33-6 Relevant articles

    Synthesis method and application of vidarabine monophosphate

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    Paragraph 0074; 0084-0086, (2021/07/28)

    The invention belongs to the field of me...

    Production process of vidarabine monophosphate

    -

    , (2019/01/23)

    The invention belongs to the technical f...

    Preparation method of vidarabine monophasphate

    -

    Page/Page column 5; 6; 7, (2018/03/25)

    The invention discloses a preparation me...

    Preparation method of vidarabine monophosphate

    -

    Paragraph 0015; 0016; 0017, (2017/07/19)

    The invention provides a preparation met...

    29984-33-6 Process route

    5'-adenosine monophosphate
    61-19-8,24937-83-5,67583-85-1

    5'-adenosine monophosphate

    5,7-Dimethoxycoumarin radical cation

    5,7-Dimethoxycoumarin radical cation

    Limettin
    487-06-9

    Limettin

    Phosphoric acid mono-[(2R,3S,4R,5R)-5-(6-amino-purin-9-yl)-3,4-dihydroxy-tetrahydro-furan-2-ylmethyl] ester
    61-19-8,16955-44-5,21138-45-4,21138-49-8,26524-56-1,26798-57-2,29740-88-3,29984-33-6,56552-99-9,56942-19-9,79026-75-8,147201-06-7

    Phosphoric acid mono-[(2R,3S,4R,5R)-5-(6-amino-purin-9-yl)-3,4-dihydroxy-tetrahydro-furan-2-ylmethyl] ester

    Conditions
    Conditions Yield
    With potassium phosphate buffer; In water; pH=7; Kinetics;
    morpholine
    110-91-8,99108-56-2

    morpholine

    vidarabine monophosphate
    29984-33-6,24937-83-5,67583-85-1

    vidarabine monophosphate

    Conditions
    Conditions Yield

    29984-33-6 Upstream products

    • 58-61-7
      58-61-7

      L-adenosine

    • 5536-17-4
      5536-17-4

      arabinosyl adenine

    • 78-40-0
      78-40-0

      triethyl phosphate

    • 52940-98-4
      52940-98-4

      6-acetylamino-9-[O 3 -acetyl-O 5 -phosphono-O 2 -(toluene-4-sulfonyl)-β-D -ribofuranosyl]-7,9-dihydro-purin-8-one

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