Diethyl cyanomethylphosphonate
- Name: Diethyl cyanomethylphosphonate
- CAS: 2537-48-6
- Purity: 99%
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Description
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1.What is the Diethyl cyanomethylphosphonate ?
Diethyl cyanomethylphosphonate is a versatile chemical and medical intermediate, characterized as a clear colorless to light yellow liquid. It is widely recognized for its utility as a modified Wittig reagent in organic synthesis, particularly for the preparation of substituted nitriles, amides, and heterocyclic derivatives.
Diethyl cyanomethyl phosphonate is used as an intermediate in Horner-Emmons reaction for the synthesis of substituted nitriles and their amide and heterocyclic derivatives. It is known as a modified Wittig reagent used in the preparation of alpha, beta-unsaturated nitriles from ketones or aldehydes like 3-hydroxy-3-methylbutanal. It reacts with epoxides and nitrones to prepare cyano-substituted cyclopropanes and aziridines respectively. It is actively involved in the synthesis of alpha-arylated alkanenitriles via reaction with aryl iodides in presence of CuI.
2.What is the CAS number for Diethyl cyanomethylphosphonate ?
The CAS number of Diethyl cyanomethylphosphonate is 2537-48-6.
More information of Diethyl cyanomethylphosphonate 2537-48-6 are:
CAS?Number
2537-48-6 Density
1.122 g/cm3 Boiling Point
305.2 °C at 760 mmHg Flash Point
117.3 °C Vapor Pressure
0.000831mmHg at 25°C Refractive Index
n20/D 1.434(lit.) HS CODE
29310095 PSA
69.13000 LogP
1.77608 3.What is the molecular formula of Diethyl cyanomethylphosphonate ?
The chemical formula of?Diethyl cyanomethylphosphonate is C6H12NO3P which containing 6 Carbon atoms,12 Hydrogen atoms,1 Nitrogen atoms,3 Oxygen atoms and 1 Phosphorus atoms,and the molecular weight, and the molecular weight of Diethyl cyanomethylphosphonate is 177.14
4.What is Diethyl cyanomethylphosphonate(2537-48-6)used for?
Diethyl cyanomethylphosphonate is a versatile chemical and medical intermediate, characterized as a clear colorless to light yellow liquid. It is widely recognized for its utility as a modified Wittig reagent in organic synthesis, particularly for the preparation of substituted nitriles, amides, and heterocyclic derivatives.
InChI:InChI=1/C6H12NO3P/c1-3-9-11(8,6-5-7)10-4-2/h3-4,6H2,1-2H3
Relevant articles related to Diethyl cyanomethylphosphonate:
Article
Source
One-step Synthesis of Stabilized Phosphonates
Kandil, Ali A.,Porter, Terence M.,Slessor, Keith N.
, p. 411 - 413 (1987)
Design, synthesis and SAR study of novel sulfonylureas containing an alkenyl moiety
Wei, Wei,Cheng, Dandan,Liu, Jingbo,Li, Yuxin,Ma, Yi,Li, Yonghong,Yu, Shujing,Zhang, Xiao,Li, Zhengming
, p. 8356 - 8366 (2016/09/09)
5.Top Quality Chinese Manufacturer supply 2537-48-6 Diethyl cyanomethylphosphonate
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