2-Amino-5-bromo-6-methylpyridine
- Name:2-Amino-5-bromo-6-methylpyridine
- CAS:42753-71-9
- Purity:99%
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Description
Quality Factory Hot Selling 2-Amino-5-bromo-6-methylpyridine 42753-71-9 with Fast Shipping
- Molecular Formula:C6H7BrN2
- Molecular Weight:187.039
- Appearance/Colour:Light yellow crystal
- Vapor Pressure:0.0534mmHg at 25°C
- Melting Point:79-84 °C(lit.)
- Refractive Index:1.5500 (estimate)
- Boiling Point:234.3 °C at 760 mmHg
- PKA:4.80±0.37(Predicted)
- Flash Point:95.5 °C
- PSA：38.91000
- Density:1.593 g/cm3
- LogP:2.31590
2-Amino-5-bromo-6-methylpyridine(Cas 42753-71-9) Usage
InChI:InChI=1/C6H7BrN2/c1-4-5(7)2-3-6(8)9-4/h2-3H,1H3,(H2,8,9)/p+1
42753-71-9 Relevant articles
Directing Group Enables Electrochemical Selectively Meta-Bromination of Pyridines under Mild Conditions
Wu, Yanwei,Xu, Shanghui,Wang, Hong,Shao, Dongxu,Qi, Qiqi,Lu, Yi,Ma, Li,Zhou, Jianhua,Hu, Wei,Gao, Wei,Chen, Jianbin
, p. 16144 - 16150 (2021/07/19)
Without the use of catalysts and oxidant...
Synthesis method of nitrogen-containing deuterated methyl compound
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Paragraph 0096-0103, (2020/04/17)
The invention discloses a synthesis meth...
multi-links class PI3K inhibitors (by machine translation)
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Paragraph 0271; 0272; 0273, (2016/10/09)
The invention belongs to the field of me...
NOVEL COMPOUNDS AS REARRANGED DURING TRANSFECTION (RET) INHIBITORS
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Page/Page column 123; 124, (2016/04/20)
This invention relates to novel compound...
42753-71-9 Process route
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3430-17-9
2-bromo-3-picoline
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42753-71-9
5-bromo-6-methyl-pyridin-2-ylamine
ConditionsConditions Yield With sodium amide; In 5,5-dimethyl-1,3-cyclohexadiene; at 118 - 120 ℃; for 1h; Time; Concentration; Inert atmosphere;90.1%
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1824-81-3
2-Amino-6-methylpyridine
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42753-71-9
5-bromo-6-methyl-pyridin-2-ylamine
ConditionsConditions Yield With 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione; In dichloromethane; at -5 ℃; for 3h;100%
With dihydrogen peroxide; 1-butylpyridinium bromide; toluene-4-sulfonic acid; In 1,2-dimethoxyethane; at 80 ℃; for 24h; regioselective reaction; Schlenk technique; Inert atmosphere; Green chemistry;85%
With 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione; In dichloromethane; at -10 - 20 ℃; for 2 - 3h; Product distribution / selectivity;84%
With sulfuric acid; bromine; In (2S)-N-methyl-1-phenylpropan-2-amine hydrate; water;55%
With N-Bromosuccinimide; In tetrahydrofuran; at 0 - 20 ℃; for 3h; Time; Inert atmosphere;48.2%
With bromine; In acetic acid; at 25 ℃; for 16h;42.8%
With N-Bromosuccinimide; In methanol; at 0 - 20 ℃; for 17h; Inert atmosphere;34.7%
With sulfuric acid; bromine;With tetrabutylammomium bromide; lithium perchlorate; In acetic acid; acetonitrile; at 25 ℃; for 8h; regioselective reaction; Electrolysis; Inert atmosphere;42753-71-9 Upstream products
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1824-81-3
2-Amino-6-methylpyridine
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3430-17-9
2-bromo-3-picoline
42753-71-9 Downstream products
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54923-31-8
5-bromo-2-hydroxy-6-methylpyridine
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68957-50-6
2-amino-5-bromo-6-methyl-3-nitropyridine
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183428-90-2
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