4-Fluoromandelic acid
- Name: 4-Fluoromandelic acid
- CAS: 395-33-5
- Purity: 99%
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Description
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1.What is the 4-Fluoromandelic acid ?
Used in Pharmaceutical Synthesis:
4-Fluoromandelic acid is utilized as an intermediate in the pharmaceutical industry for the synthesis of various drugs and organic compounds. Its unique structure allows for the creation of new molecules with potential therapeutic applications.
Used as a Chiral Resolving Agent in Analytical Chemistry:
In the field of analytical chemistry, 4-Fluoromandelic acid serves as a chiral resolving agent. It aids in the separation of enantiomers, which is crucial for the development and analysis of chiral drugs, as different enantiomers can have distinct biological activities.
Used as a Precursor in the Synthesis of Complex Molecules:
4-Fluoromandelic acid also acts as a precursor in the synthesis of more complex molecules, contributing to the advancement of organic chemistry and the creation of new compounds with specific properties and applications.
Used in Research and Development:
Due to its distinctive chemical and physical properties, 4-Fluoromandelic acid is employed in research and development settings to explore new chemical reactions, investigate the effects of fluorination on molecular behavior, and develop innovative applications in various industries.-
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403-42-9
1-(4-fluorophenyl)ethanone
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456-22-4
4-Fluorobenzoic acid
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32222-45-0,52923-25-8,52950-15-9,395-33-5
4-fluoromandelic acid
ConditionsConditions Yield With sodium hypochlorite; hydroxide; In water; for 20h; Product distribution; Rate constant; Ambient temperature; variation of time and reagent concentration; kinetic measurements at 25 deg C;5 % Spectr.
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133721-87-6,176485-58-8
2-(4-fluorophenyl)-2-hydroxyacetonitrile
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32222-45-0,52923-25-8,52950-15-9,395-33-5
4-fluoromandelic acid
ConditionsConditions Yield With hydrogenchloride; water; at 20 ℃; for 21h; Reflux;90%
With hydrogenchloride; for 19h; Ambient temperature;With hydrogenchloride; water; In 1,4-dioxane; for 6h; Reflux;With hydrogenchloride; water; for 2h; Reflux;With hydrogenchloride; water; at 70 ℃;2.What is the CAS number for 4-Fluoromandelic acid ?
The CAS number of 4-Fluoromandelic acid is 395-33-5.
More information of 4-Fluoromandelic acid 395-33-5 are:
CAS?Number
395-33-5 Density
1.425 g/cm3 Melting Point
136-137 °C Boiling Point
322.4 °C at 760 mmHg Flash Point
148.8 °C Vapor Pressure
0.000115mmHg at 25°C HS CODE
2918199090 PSA
57.53000 LogP
0.94370 Pka
3.17±0.10(Predicted) 3.What are another words for 4-Fluoromandelic acid ?
Synonyms?for?4-Fluoromandelic acid 395-33-5:Mandelicacid, p-fluoro- (7CI,8CI);2-(4-Fluorophenyl)-2-hydroxyacetic acid;2-Hydroxy-2-(4-fluorophenyl)acetic acid;NSC 73990;p-Fluoromandelic acid;
4.What is the molecular formula of 4-Fluoromandelic acid?
The chemical formula of ?4-Fluoromandelic acid is?C8 H7 FO3 which containing 8 Carbon atoms,7 Hydrogen atoms,1 Fluorine atoms and 3 Oxygen atoms,and the molecular weight of??4-Fluoromandelic acid?is 170.14.
5.What is 4-Fluoromandelic acid (395-33-5) used for?
4-Fluoromandelic acid, also known as 4-FMA, is a chemical compound with the molecular formula C8H7FO3. It is a derivative of mandelic acid, featuring a fluorine atom attached to the benzene ring. 4-Fluoromandelic acid is recognized for its unique chemical and physical properties, which render it valuable in a variety of research and industrial applications, particularly as an intermediate in the synthesis of pharmaceuticals and other organic compounds.
InChI:InChI=1/C8H7FO3/c9-6-3-1-5(2-4-6)7(10)8(11)12/h1-4,7,10H,(H,11,12)/p-1/t7-/m1/s1
Relevant articles related to 4-Fluoromandelic acid:
Article
Source
The Synthesis of Chiral α-Aryl α-Hydroxy Carboxylic Acids via RuPHOX-Ru Catalyzed Asymmetric Hydrogenation
Guo, Huan,Li, Jing,Liu, Delong,Zhang, Wanbin
, p. 3665 - 3673 (2017/09/11)
Kinetic resolution of mandelate esters via stereoselective acylation catalyzed by lipase PS-30
Chen, Peiran,Yang, Wenhong
supporting information, p. 2290 - 2294 (2014/04/17)
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